Warning Cookies are used on this site to provide the best user experience. If you continue, we assume that you agree to receive cookies from this site. OK

Biocompatible Coating Polymers

Biocompatible coating polymer suppresses cell and protein adsorption on the surface.

Lipidure®-CM coated surface is covered with phosphorylcholine units. Any cells and proteins do not adhere to the surface. Lipidure® can be coated on plastics such as PET, PMMA, PS (PSt), PU, PC, PE, and PP, glass, ceramics, and metals such as SUS, titanium, and gold.

Chemical structure of biocompatible coating polymer

Chemical structure of Lipidure-CM


Coating Method of biocompatible coating polymerCoating Method of Lipidure^CM


Available substrate of biocompatible coating polymer

Lipidure-CM5206 can be coated on the following materials


Feature of biocompatible coating polymer


Technical data of biocompatible coating polymer

・Suppression of protein adsorption with biocompatible coating polymer

<<Method>>

1. Prepare well plate coated with Lipidure®-CM5206
2. Add HRP-IgG conjugate solution into each well
3. Incubate for 1 hr at 25 ºC
4. Rinse three times with 0.05 % Tween20/Dulbeco’s PBS
5. Add of 3,3’,5,5’-tetramethylbenzidine solution into each well
6. Measure absorbance at 450 nm

・Suppression of cell adsorption with biocompatible coating polymer

<<Method>>

1. Prepare well plate coated with Lipidure®-CM5206
2. Seed macrophage in well plate at 3.3x105 cells/well
3. Incubate for 1 hr at 37 ºC in 5% CO2 atmosphere
4. Rinse off with Dulbeco’s PBS
5. Fix with glutaraldehyde and Observation by SEM

・Hemo-compatibility of biocompatible coating polymer

<<Method>>

1. Prepare artificial vascular coated with Lipidure®-CM5206
2. Rabbit blood was flowed in Lipidure®-CM5206 treated artificial vascular
3. Rinse artificial vascular with buffer solution
4. Take photo of inside of artificial vascular