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LIPIDURE®, Biocompatible Polymer for Cosmetics

What is Lipidure?

Cosmetic ingredients for skin care and hair care with high moisturizing effect

Lipidure® is a biocompatible polymer consists of 2-methacryloyloxtethyl phosphorylcholine (MPC: the bellow figure) which has the same structure as polar group of phospholipid*, showing high hydrophilic nature and extremely low toxicological data. Also, since MPC can be co-polymerized with other monomers in order to adjust to the purpose of use, Lipidure® is useful for wide variety of applications such as cosmetic ingredients, eye care ingredients, oral care ingredients, and coating material of medical devices. On this page, we will focus on specific Lipidure® designed for cosmetic ingredients such as skin care, hair care and make-up emphasizing its high biocompatibility and high moisturizing effect.

*Phospholipid is a major component of cell membranes.

Methacryloyloxyethyl Phosphorylcholine (MPC)
Methacryloyloxyethyl Phosphorylcholine (MPC)

polymerization of MPC
Lipidure Structure


Lipidure® is made from MPC monomer.

Why is Lipidure® so biocompatible?

Cells are the smallest units constituting a living body and engage in diverse activities to sustain the life. Cell membrane which separates inside and outside of the cells plays important rolls such as homeostasis of the cells, selective permeability of substances, and inter-cellular communication. The cell membrane is consisted of phospholipids which has hydrophilic head (phosphorylcholine: yellow cube in the bellow figure) and lipophilic tails (orange bars in the bellow figure). Lipidure® has the phosphorylcholine in its molecule as illustrated in the bellow figure. Lipidure® is, so to speak, a mimic cell membrane and this molecular structure is the key for high hydrophilic nature and extremely low toxicity of Lipidure®.

Cell membrane and Lipidure

Fundamental Features of Lipidure® for cosmetic ingredients

Lipidure® is useful for cosmetic ingredients of skin care and hair care with following features.

  • High moisturizing effect
  • High Safety
  • High biocompatibility
  • High hydrophilicity

In detail, please visit following pages. We would like to show you technical data such as moisturizing effect, waterproof property, reduction of irritation from irritants, hair repair effect, reduction of hair friction, restoration of hair strength, suppression of static electricity on hair, and so on.

Product Line of Lipidure® for cosmetic ingredients


Chemical structure




Lipidure HM

Polyphosphorylcholine Glycol Acrylate

Skin Care


Lipidure PMB



Product line of Lipidure


Hair Care


Lipidure S


Make up

Skin Care


Hair Care

LIPIDURE®-HM and LIPIDURE-PMB® have been authorized once as quasi drugs.

Safety Tests

The safety of LIPIDURE® has been proven by the following tests.

1. Acute toxicity test
2. Skin primary irritation test
3. Continuous skin irritation test
4. Sensitization test
5. Photo toxicity test
6. Photosensitization test
7. Eye irritation test
8. Mutagenicity test
9. Human patch test