NOF has developed novel degradable PEGs that have enzyme cleavable peptide linkers. Degradable PEGs have the same blood circulation time as non-degradable PEGs and are removed from the body faster than non-degradable PEGs, because they are cleaved to lower molecular weight PEG in cell.
Degradation test in vitro
Pharmacokinetic test in vivo
Linear Type Degradable PEGs
SUNBRIGHT® LP4 Series
Branched Type Degradable PEGs
2-arm Branched PEGs (SUNBRIGHT® BP2 series)
4-arm Branched PEGs (SUNBRIGHT® 4BP2 series)