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PEG Phospholipids

PEG Phospholipids

PEGylated lipids can be applied to liposomal drug formulations to prolong the plasma half-life of the drugs. Coating of the liposomal surface with polyethylene glycol would suppress the uptake of the drug by the reticuloendothelial system, thereby prolonging the half-life of the drug in the plasma.

PEG-modified lipids can also be used as emulsifiers and stabilizers of microspheres in aqueous solutions.

PEG-phospholipids

PEG phospholipids of the carbamate-linked type are resistant to hydrolysis, and therefore are used for commercial production of PEGylated liposomes. As NOF employs its own high-quality activated PEGs and phospholipids, high-quality PEG phospholipids can be supplied.

PEG-phospholipids

SUNBRIGHT® DSPE-020CN

Acronym: DSPE-PEG 2,000
Chemical Name: N-(Methylpolyoxyethylene oxycarbonyl)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
CAS#: 247925-28-6
PEG chain Molecular weight: 2000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 1g / 10g

SUNBRIGHT® DSPE-050CN

Acronym: DSPE-PEG 5,000
Chemical Name: N-(Methylpolyoxyethylene oxycarbonyl)-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
CAS#: 247925-28-6
PEG chain Molecular weight: 5000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 1g / 10g

SUNBRIGHT® PP-020CN*

Acronym: DPPE-PEG 2,000
Chemical Name: N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine, sodium salt
CAS#: Not available
PEG chain Molecular weight: 2000
Alkyl composition: R₁COO= C16:0, R₂COO= C16:0

Packaging size: 1g / 10g

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SUNBRIGHT® PM-020CN*

Acronym: DMPE-PEG 2,000
Chemical Name: N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine, sodium salt
CAS#: None
PEG chain Molecular weight: 2000
Alkyl composition: R₁COO= C14:0, R₂COO= C14:0

Packaging size: 1g / 10g

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SUNBRIGHT® PP-050CN*

Acronym: DPPE-PEG 5,000
Chemical Name: N-(Carbonyl-methoxypolyethyleneglycol 2000)-1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine, sodium salt
CAS#: Not available
PEG chain Molecular weight: 5000
Alkyl composition: R₁COO= C16:0, R₂COO= C16:0

Packaging size: 1g / 10g

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SUNBRIGHT® DSPE-020GL2U*

Acronym: DSPE-2arm PEG 2,000
Chemical Name: N-[Carbonyl-2’,3’-Bis(methoxypolyethyleneglycol 2000)]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
CAS#:
PEG chain Molecular weight: 2000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

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SUNBRIGHT® DSPE-050GL2U*

Acronym: DSPE-2arm PEG 5,000
Chemical Name: N-[Carbonyl-2’,3’-Bis(methoxypolyethyleneglycol 5000)]-1,2-distearoyl-sn-glycero-3-phosphoethanolamine, sodium salt
CAS#:
PEG chain Molecular weight: 5000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 1g / 10g

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Activated PEG phospholipids

Phospholipid-PEG-NH2

SUNBRIGHT® DSPE-034PA*

Acronym: DSPE-PEG-NH₂
Chemical Name: N-(aminopropyl polyethyleneglycol)carbamyl-distearoylphosphatidyl-ethanolamine
CAS#: 1251930-98-9
PEG chain Molecular weight: 3400
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

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SUNBRIGHT® DSPE-020PA

Acronym: DSPE-PEG-NH₂
Chemical Name: N-(aminopropyl polyethyleneglycol)carbamyl-distearoylphosphatidyl-ethanolamine
CAS#: 1251930-98-9
PEG chain Molecular weight: 2000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

SUNBRIGHT® DSPE-050PA

Acronym: DSPE-PEG-NH₂
Chemical Name: N-(aminopropyl polyethyleneglycol)carbamyl-distearoylphosphatidyl-ethanolamine
CAS#: 1251930-98-9
PEG chain Molecular weight: 5000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

Phospholipid-PEG-MAL

SUNBRIGHT® DSPE-050MA*

Acronym: DSPE-PEG-MAL
Chemical Name: N-[(3-Maleimide-1-oxopropyl)aminopropyl polyethyleneglycol-carbamyl] distearoylphosphatidyl-ethanolamine
CAS#: 1378941-43-5
PEG chain Molecular weight: 5000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

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SUNBRIGHT® DSPE-020MA01

Acronym: DSPE-PEG-MAL
Chemical Name: N-[(3-Maleimide-1-oxopropyl)aminopropyl polyethyleneglycol-carbamyl] distearoylphosphatidyl-ethanolamine
CAS#: 1378941-43-5
PEG chain Molecular weight: 2000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

SUNBRIGHT® DSPE-034MA

Acronym: DSPE-PEG-MAL
Chemical Name: N-[(3-Maleimide-1-oxopropyl)aminopropyl polyethyleneglycol-carbamyl] distearoylphosphatidyl-ethanolamine
CAS#: 1378941-43-5
PEG chain Molecular weight: 3400
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

Phospholipid-PEG-NHS

SUNBRIGHT® DSPE-020GS

Acronym: DSPE-PEG-NHS
Chemical Name: 3-(N-succinimidyloxyglutaryl)aminopropyl, polyethyleneglycol-carbamyl distearoylphosphatidyl-ethanolamine
CAS#: 1244784-44-8
PEG chain Molecular weight: 2000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

SUNBRIGHT® DSPE-050GS*

Acronym: DSPE-PEG-NHS
Chemical Name: 3-(N-succinimidyloxyglutaryl)aminopropyl, polyethyleneglycol-carbamyl distearoylphosphatidyl-ethanolamine
CAS#: 1244784-44-8
PEG chain Molecular weight: 5000
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

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SUNBRIGHT® DSPE-034GS*

Acronym: DSPE-PEG-NHS
Chemical Name: 3-(N-succinimidyloxyglutaryl)aminopropyl, polyethyleneglycol-carbamyl distearoylphosphatidyl-ethanolamine
CAS#: 1244784-44-8
PEG chain Molecular weight: 3400
Alkyl composition: R₁COO= C18:0, R₂COO= C18:0

Packaging size: 0.1g / 1g / 10g

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Phospholipid-PEG-ALD

SUNBRIGHT® DSPE-034AL*

Acronym: DSPE-PEG-NHS
Chemical Name: 3-(N-succinimidyloxyglutaryl)aminopropyl, polyethyleneglycol-carbamyl distearoylphosphatidyl-ethanolamine
CAS#:
PEG chain Molecular weight: 3,400

Packaging size: 0.1g / 1g / 10g

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